Our natural timer

Published : 01/23/2019 16:17:55
Categories : News

Sleeping is an essential human need and is strongly correlated to our circadian rhythm, also known as a biological clock. In fact this natural timer helps our body to recognize drowsiness and vigil within 24 hours.

If we were able to be constant in going to bed by 11 or 24 and waking up at the same time every day, after about 7-8 hours of sleep (possibly in the dark), we would keep our circadian rhythm stable thus maximizing our productivity and making a quality sleep.

There is, however, another ally of rest! Let's find out who is ...

What is melatonin?

Melatonin is a hormone produced by the pineal gland, which helps regulate the circadian rhythm.

Our brain usually begins to secrete melatonin around 9:00 pm, which is when most people go to bed. As the quantity of this hormone increases, our body begins to feel a progressive need for sleep, thus allowing us to optimize the period of sleep.

To do this correctly, we must be exposed to light during the day, as the production of melatonin depends on how much light it absorbs our body. If you stay awake beyond darkness, the light emitted by electrical devices (especially LED or blue light) hinders your body's ability to produce melatonin. The use of these devices should be stopped one hour before bed, to help increase melatonin production and maintain a constant circadian rhythm. This problem of altered melatonin production also afflicts those who practice a profession that involves night shifts, as it worsens the functioning of the circadian rhythm: in fact some biological signals in the body are produced electrically by day or by night. Failure to respect the circadian rhythm (and therefore the lack of melatonin) does nothing but alter these biochemical and metabolic pathways, with a negative repercussion on the aging process and on many pathologies (as demonstrated by a large scientific production).

Based on published research, it has been discovered that melatonin has three main functions:

• It controls the circadian rhythm: melatonin works by helping sleep, normalizing the circadian rhythm and stimulating our body to seek night rest. It is therefore a hormone that sends signals in many cerebral biochemical fields, but also outside the central nervous system.

• It has a clear antioxidant function: recent studies have found that melatonin also works as an antioxidant. In particular, it can help different metabolic aspects of our brain, cardiovascular and gastrointestinal well-being. In some cases, it can even support cancer prevention.

• Optimize the functionality of our immune system: melatonin can help our immune system in various ways. In one study, the researchers suggested that melatonin can help improve the treatment of bacterial diseases such as tuberculosis. In another study, melatonin was defined as a potential tool against inflammation, autoimmune diseases and diabetes. In fact, melatonin regulates the production of cortisol, a stress hormone necessary and useful if produced as needed for a short time, harmful in the form of chronic hyper-production. A decrease in melatonin inevitably leads to an excess of cortisol with negative repercussions on multiple psycho-organic processes of our body.


A proper lifestyle helps ensure that our body produces enough melatonin. Here we list some measures and behaviors useful for this purpose:

• To avoid using electronic devices one hour before sleep: cell phones, TVs and computers emit blue light and exposure to it induces errors in the circadian rhythm that potentially damage our cells (mitochondria in the first place). By avoiding exposure to these devices for at least an hour before falling asleep, our body can produce the necessary melatonin to help us induce sleep at the desired time.

• To make sure you get regular exposure to sunlight: getting regular exposure to the sun during the day helps our body optimize the rate of cessation and production of melatonin.

• To seek sleep in complete darkness: if possible, try removing light sources from our room to improve sleep quality. The slightest exposure to light can interfere with the production of melatonin in our body.

• To remove sources of electromagnetic fields (EMF) in the bedroom: the electromagnetic fields emitted by some devices such as Internet routers can disturb the production of melatonin in the pineal gland. Ideally, before going to sleep, you should turn off the wireless router and other wireless devices connected to the Internet.

• To introduce the following foods containing melatonin in the diet: meat from animals fed with grass (lamb, beef and pork), wild salmon, chicken and eggs, milk, pineapple, banana, apple, pomegranate, mulberry, cherries, grapes, onion, garlic, cauliflower, turnip, cucumber, carrot, radish, beetroot, tomatoes, seeds (flax, sunflower, fennel, mustard, alfalfa, celery and fenugreek) and walnuts (pistachio, almonds and walnuts).

Objectively, above 50 years of age, the natural production of melatonin gradually decreases until almost to cancel over 70-80 years. This progressive lack induces more and more individuals to a supplementation with melatonin supplements, natural and useful to compensate for its lack inevitably linked to the advancing age. This assumption becomes in fact useful even for individuals under 50-60 years who for incorrect work or behavioral reasons reduce their natural production of melatonin.

Melatonin supplements

Scientific research has shown that melatonin can have multiple effects, resulting in an excellent principle for the more general aging process and the widespread chronic degenerative diseases that characterize the average age population and above 60-70 years above all.

Melateon®: food supplement based on Melatonin

Melatonin supplements are very common and have become commonplace. Melatonin in drops or tablets is taken mainly for sleep problems: difficulty falling asleep, insufficient or disturbed sleep or jet lag syndrome (time zone). As already highlighted above, the many other effects of melatonin on the human body make nutraceuticals based on this substance a useful complement in many situations for a better balance and well-being of the individual.

Proeon has created Melateon®, a melatonin supplement in drops, unique in composition, dose and quality. The possibility of taking melatonin in drops in fact makes the dosage easily variable, as well as sublingual administration makes this substance more rapidly and homogeneously available for the body, compared to the classic melatonin tablets / capsules subject to gastric-digestive problems.

Melateon® is indicated for jet lag syndrome and sleep disorders, but it can also be useful to support the regulation of the Psycho-Neuro-Endocrine-Immune (PNEI) system and therefore in chronic stress syndromes, from excessive oxidative stress and over training in athletes. Finally, it should be remembered that the formulation of Melateon makes the vial sufficiently suitable for a 60-90 days intake, with an excellent cost/dosage ratio.

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