Miteon Plus Bibliography

Miteon PLUS Bibliography

You can find more information on the active ingredients of Miteon PLUS by consulting:

1. Safety of pyrroloquinoline quinone disodium salt as a novel food pursuant to Regulation (EC) No 258/97.Turck D., Bresson JL, Burlingame B., et al.EFSA Journal 2017;15(10):5058.
2. Effects of dietary pyrroloquinoline quinone disodium on growth, carcass characteristics, redox status, and mitochondria metabolism in broilers.Wang J, Zhang HJ, Samuel KG, et al.Poultry Science, 2015; 94, 215–225.
3. Antioxidant and pro-oxidant properties of pyrroloquinoline quinone (PQQ): implications for its function in biological systems.He K, Nukada H, Urakami T, Murphy MP.Biochemical Pharmacology, 2003; 65, 67–74.
4. Dietary pyrroloquinoline quinone (PQQ) alters indicators of inflammation and mitochondrial-related metabolism in human subjects.Harris CB, Chowanadisai W, Mishchuk DO, et al.Journal of Nutritional Biochemistry, 2013; 24, 2076–2084.
5. Pyrroloquinoline quinone disodium salt in Natural Health ProductsIngredients Database.Health Canada, Natural Health Products Directorate (NHPD).Health Canada, 2016.
6. Specific detection of quinoproteins by redox-cycling staining.Paz MA, Flückiger R, Boak A, Kagan HM, Gallop PM.J Biol Chem. 1991 Jan 15;266(2):689-92.
7. Redox-cycling detection of dialyzable pyrroloquinoline quinone and quinoproteins.Flückiger R, Paz MA, Gallop PM.Methods Enzymol. 1995:258:140-9.
8. Potential physiological importance of pyrroloquinoline quinone.Rucker R, Chowanadisai W, Nakano M.Alternative Medicine Review, 2009; 14, 268–277.
9. Pyrroloquinoline quinone disodium salt improves higher brain function.Koikeda T, Nakano M, Masuda K.Shinryo To Shinyaku [Medical Consultation & New Remedies], 2011; 48, 519–527.
10. The safety of pyrroloquinoline quinone disodium in older adults with self-reported memory loss.Krieger D, Kalman D, Feldman S, Samson A, Nader S.QPS MRA (Miami Research Associates), 2016.
11. Effect of the Antioxidant Supplement Pyrroloquinoline Quinone Disodium Salt (BioPQQ™) on Cognitive Functions.Itoh Y, Hine K, Miura H, et al.Adv Exp Med Biol. 2016:876:319-325.
12. Effect of vitamin E on learning and memory deficit in aged rats.Takatsu H, Owada K, Abe K, Nakano M, Urano S.J Nutr Sci Vitaminol (Tokyo). 2009;55(5):389-93.
13. Levels of pyrroloquinoline quinone in various foods.Kumazawa T, Sato K, Seno H, Ishii A, Suzuki O.Biochemical Journal, 1995; 307(Pt. 2), 331–333.
14. Meta-analysis, metaphysics and mythology: Scientific and clinical perspective on the controversies regarding vitamin E for the prevention and treatment of disease in humans.Houston M.Journal of the American Nutraceutical Association 2005; Vol. 8 No. 1.
15. Antioxidantinduced regression of carotidstenosis overthree-years.Kooyenga DK, Geller M, Watkins TR, Bierenbaum ML.Proceedings of the 16th International Congress of Nutrition. Montreal, July 29, 1997.
16. Tocotrienol is the most effective vitamin E for reducing endothelial expression of adhesion molecules and adhesion to monocytes.Theriault A, Chao JT, Gapor A.Atherosclerosis 2002; 160 (1): 21-30.
17. Inhibitory effect of delta-tocotrienol, a HMG CoA reductase inhibitor, on monocyte-endothelial cell adhesion.Chao JT, Gapor A, Theriault A.J. Nutr.Sci.VitaminoL (Tokyo) 2002; 48 (5): 332-337.
18. Tocotrienols reduce 25-hydroxycholesterol-induced monocyte-endothelial cell interaction by inhibiting the surface expression of adhesion molecules.Naito Y et al.Atherosclerosis 2005; 180 (1): 19-25.
19. Coenzyme Q10 in the treatment of hypertension: A meta-analysis of the clinical trials.Rosenfeldt FL et al.J. Hum. Hypertens. 2007; 21(4): 297-306.
20. Nitric oxide synthase activity in blood vessels of spontaneously hypertensive rats: antioxidant protection by gamma-tocotrienol.Newaz MA, Yousefipour Z, Nawal N, Adeeb N.J. PhysioL PharmacoL 2003; 54 (3): 319-327.
21. Tocotrienol: a review of its therapeutic potential.Theriault A, Chao JT, Wang Q, Gapor A, Adeli K.Clinical biochemistry 1999; 32.5: 309-319.
22. Tocotrienol: the natural vitamin E to defend the nervous system?Sen CK, Khanna S, Roy S.Ann. NY Acad.Sci. 2004; 1031:127-42.
23. Neuroprotective properties of the natural vitamin E alpha-tocotrienol.Khanna S et al.Stroke 2005; 36 (10): 2258-2264.
24. The role of tocotrienols in inflammatory diseases.Aggarwal BA.Cytokine Research Laboratory, Department of Experimental Therapeutics, The University ofTexas M. D. Anderson Cancer Center, Houston, Texas.
25. Tocotrienol mechanism in cholesterol-lowering.DeBose-Boyd R.UTSouthwestern Medical Center, Dallas, Texas.
26. Inhibitory effect of tocotrienol on eukaryotic DNA polymerase lambda and angiogenesis.Mizushina Y et al.Biochem. Biophys. Res.Commun. 2006; 339 (3): 949-955.
27. In vivo angiogenesis is suppressed by unsaturated vitamin E, tocotrienol.Nakagawa K, Shibata A, Yamashita S, et al.J. Nutr. 2007; 137:1938-1943.
28. Tocotrienols: Vitamin E beyond Tocopherols.Tan B, Watson RR, Preedy VR.
29. Mevalonate-suppressive tocotrienols for cancer chemoprevention and adjuvant therapy.Huanbiao M.Department of Nutrition and Food Sciences, Texas Woman's University, Denton, Texas.
30. On the superiority ofhypomethyl (delta- and gamma-) tocotrienols as anticancer agentsin neu-positive breast cancer.Ciffolilli S, Legnaioli S, Piroddi M, Pierpaoli E, Provinciali M, Galli F.
31. Antiproliferative and apoptotic effects of tocopherols and tocotrienols on preneoplastic and neoplastic mouse mammary epithelial cells.McIntyre BS et al.Proc. Soc. Exp. Biol. Med. 2000; 224 (4): 292-301.
32. Tocotrienols potentiate lovastatin-mediated growth suppression in vitro and in vivo.McAnally JA et al.Exp. Biol. Med. (Maywood) 2007; 232 (4): 523-531.
33. Tocotrienols inhibit the growth of human breast cancer cells irrespective of estrogen receptor status.Nesaretnam K. et al.Lipids 1998; 33 (5): 461-469.
34. Gamma-tocotrienol metabolism and antiproliferative effect in prostate cancer cells.Conte C. et al.Ann. NY Acad.Sci. 2004; 1031, 391-394.
35. Down-regulation of telomerase activity in DLD-1 human colorectal adenocarcinoma cells by tocotrienol.Eitsuka T, Nakagawa K, Miyazawa T.Biochem. Biophys. Res. Commun. 2006; 348 (1): 170-175.
36. Delta-tocotrienol treatment and prevention of pancreatic cancer.Malafa MP, Sebti S.Lee Moffitt Cancer Center & Research lnstitute, University of South Florida (Tampa), 2008.
37. Delta-tocotrienol treatment and prevention of pancreatic Cancer.Malafa MP, Sebti S.Lee Moffitt Cancer Center & Research Institute, University of South Florida (Tampa), 2008.
38. Apoptosis induction by gamma-tocotrienol in human hepatoma Hep3B cells.Sakai M et al.J. Nutr. Biochem. 2006; 17 (10): 672-676.
39. Vitamin E: mechanisms of action as tumor cell growth inhibitors.Kline K, Yu W, Sanders BG.J. Nutr. 2001; 131 (1): 161S-163S.
40. lnsig-dependent ubiquitination and degradation of 3-hydroxy-3-methylglutaryl coenzyme A reductase stimulated by delta- and gamma-tocotrienols.Song BL, De Bose-Boyd RA.J. Biol. Chem. 2006; 281 (35): 25054-25061.
41. Dose-response impact of various tocotrienols on serum lipid parameters in 5-week-old female chickens.Yu SG, Thomas AM, Gapor A, Tan B, Qureshi N, Qureshi AA.Lipids 2006; 41:453-461.
42. Antiproliferative and apoptotic effects of tocopherols and tocotrienols on preneoplastic and neoplastic mouse mammary epithelial cells.McIntyre BS et al.Proc. Soc. Exp. Biol. Med. 2000; 224 (4): 292-301.
43. Comparison of Coenzyme Q10 (Ubiquinone) and Reduced Coenzyme Q10 (Ubiquinol) as Supplement to Prevent Cardiovascular Disease and Reduce Cardiovascular Mortality.Fladerer JP, Grollitsch S.Current Cardiology Reports (2023) 25:1759–1767.
44. Coenzyme Q10 mitigates macrophage mediated inflammation in heart following myocardial infarction via the NLRP3/IL1β pathway.Pan W, Zhou G, Hu M, et al.BMC Cardiovasc Disord. 2024 Oct 5;24(1):537.
45. Prospects of Intravenous Coenzyme Q10 Administration in Emergency Ischemic Conditions.Kalenikova EI, Gorodetskaya EA, Povarova OV, Medvedev OS.Life (Basel). 2024 Jan 17;14(1):134.
46. Prevalence, incidence and survival of heart failure: a systematic review.Emmons-Bell S, Johnson C, Roth G.Heart. 2022 Aug 11;108(17):1351-1360.
47. Ubiquinol-10 supplementation activates mitochondria functions to decelerate senescence in senescence-accelerated mice.Tian G, Sawashita J, Kubo H, et al.Antioxid Redox Signal 2014;20(16):2606-2620.
48. Bioenergetics in clinical medicine XV. Inhibition of coenzyme Q10-enzymes by clinically used adrenergic blockers of beta-receptors.Kishi T, Watanabe T, Folkers K.Res Commun Chem Pathol Pharmacol 17:157-164 (1977).
49. Effects of coenzyme Q10 on vascular endothelial function in humans: a meta-analysis of randomized controlled trials.Gao L, Mao Q, Cao J, Wang Y, Zhou X, Fan L.Atherosclerosis. 2012;221(2):311-316.
50. The effect of Coenzyme Q10 on morbidity and mortality in chronic heart failure: results from Q-SYMBIO: a randomized double blind trial.Mortensen, S. A., Rosenfeldt, F., Kumar, A., et al.JACC. Heart Failure, 2(6), 641-649.
51. Coenzyme Q10, rosuvastatin, and clinical outcomes in heart failure: a pre-specified substudy of CORONA (controlled rosuvastatin multinational study in heart failure).McMurray JJ, Dunselman P, Wedel H, et al.J Am Coll Cardiol. 2010;56(15):1196-1204.
52. Role of coenzyme Q10 in chronic heart failure, angina, and hypertension.Tran MT, Mitchell TM, Kennedy DT, Giles JT.Pharmacotherapy. 2001;21(7):797-806.
53. Bioavailability of coenzyme Q10: An overview of the absorption process and subsequent metabolism.Mantle D, Dybring A.Antioxidants. 2020;9(5):1–12.
54. Mechanisms of Oxidative Stress in Metabolic Syndrome.Masenga S, Kabwe L, Chakulya M, Kirabo A.Int J Mol Sci [Internet]. 2023;26.
55. Distribution of antioxidants among blood components and lipoproteins: Significance of lipids/CoQ10 ratio as a possible marker of increased risk for atherosclerosis.Tomasetti M, Alleva R, Solenghi MD, Littarru GP.BioFactors. 1999;9(2–4).
56. Coenzyme Q10: Absorption, tissue uptake, metabolism and pharmacokinetics.Bhagavan HN, Chopra RK.Free Radic Res. 2006;40(5).
57. Safety assessment of coenzyme Q10 (CoQ10).Hidaka T, Fujii K, Funahashi I, Fukutomi N, Hosoe K.Biofactors. 2008.
58. Combined supplementation of Coenzyme Q10 and other nutrients in specific medical conditions.Tippairote T, Bjørklund G, Gasmi A, et al.Nutrients. 2022;14(20):1–23.
59. Coenzyme Q10 contents in foods and fortification strategies.Pravst I, Žmitek K, Žmitek J.Crit Rev Food Sci Nutr. 2010;50(4).
60. Plasma coenzyme Q10 response to oral ingestion of coenzyme Q10 formulations.Bhagavan HN, Chopra RK.Vol. 7, Mitochondrion. 2007.
61. CoQ10 and aging.De Barcelos IP, Haas RH.Biology (Basel). 2019;8(2).
62. Characterization of a polymorphism in NAD(P)H: Quinone oxidoreductase (DT-diaphorase).Traver RD, Siegel D, Beall HD, et al.Br J Cancer. 1997;75(1).
63. NAD(P)H: quinone oxidoreductase 1 (NQO1): Chemoprotection, bioactivation, gene regulation and genetic polymorphisms.Ross D, Kepa JK, Winski SL, Beall HD, Anwar A, Siegel D.Chem Biol Interact. 2000;129(1–2):77–97.
64. Genotype-phenotype relationships in studies of a polymorphism in NAD(P)H: quinone oxidoreductase 1.Siege D, McGuinness S, Winski S, Ross D.Pharmacogenetics. 1999.
65. Coenzyme Q10: The essential nutrient.Saini R.Vol. 3, Journal of Pharmacy and Bioallied Sciences. 2011.
66. Bioavailability of four oral Coenzyme Q10 formulations in healthy volunteers.Weis M, Mortensen SA, Rassing MR, et al.Mol Aspects Med. 1994;15 (SUPPL. 1).
67. Urtica dioica-Derived Phytochemicals for Pharmacological and Therapeutic Applications.Taheri Y, Quispe C, Herrera-Bravo J, et al.Evid Based Complement Alternat Med. 2022;2022:4024331.
68. Urtica spp.: Ordinary Plants with Extraordinary Properties.Kregiel D, Pawlikowska E, Antolak H.Molecules. 2018;23(7):1664.
69. Nettle extract (Urtica dioica) affects key receptors and enzymes associated with allergic rhinitis.Roschek B Jr, Fink RC, McMichael M, Alberte RS.Phytother Res. 2009 Jul;23(7):920-6.
70. Exploring the Urtica dioica Leaves Hemostatic and Wound-Healing Potential.Zouari Bouassida K, Bardaa S, Khimiri M, et al.Biomed Res Int. 2017;2017:1047523.
71. Mineral Properties and Dietary Value of Raw and Processed Stinging Nettle (Urtica dioica L.).Rutto LK, Xu Y, Ramirez E, Brandt M.Int J Food Sci. 2013;2013:857120.
72. The efficacy of stinging nettle (urtica dioica) in patients with benign prostatic hyperplasia: a randomized double-blind study in 100 patients.Ghorbanibirgani A, Khalili A, Zamani L.Iran Red Crescent Med J. 2013;15(1):9-10.
73. Dietary Plants for the Prevention and Management of Kidney Stones: Preclinical and Clinical Evidence and Molecular Mechanisms.Nirumand MC, Hajialyani M, Rahimi R, et al.Int J Mol Sci. 2018 Mar 7;19(3):765.
74. Effects of Pyrroloquinoline Quinone (PQQ) Supplementation on Aerobic Exercise Performance and Indices of Mitochondrial Biogenesis in Untrained Men.Hwang PS, Machek SB, Cardaci TD, et al.J Am Coll Nutr. 2020 Aug;39(6):547-556.
75. The Life History of Pyrroloquinoline Quinone (PQQ): A Versatile Molecule with novel Impacts on Living Systems.Naveed M, Tariq K, Sadia H, Ahmad H, Mumtaz AS.Molecular Biology 1(1): 00005.
76. Current study on Pyrroloquinoline quinone (PQQ) therapeutic role in neurodegenerative diseases.Xie T, Zhang Z, Feng M, Kong L.Mol Biol Rep. 2025 Apr 15;52(1):397.
77. Physiological importance of quinoenzymes and the O-quinone family: the case of pyrroloquinoline quinone.Stites T. E., Mitchell A. E., Rucker R. B.The Journal of Nutrition, 2006; 136(10), 2827–2834.
78. Pyrroloquinoline quinone stimulates mitochondrial biogenesis through cAMP response element-binding protein phosphorylation and increased PGC-1α expression.Chowanadisai W. et al.The Journal of Biological Chemistry, 2009; 285(1), 142–152.
79. Bioenergetic and antioxidant properties of coenzyme Q10: recent developments.Littarru G. P. & Tiano L.Molecular Biotechnology, 2007; 37(1), 31–37.
80. Effects of coenzyme Q10 and pyrroloquinoline quinone on cognitive function in the elderly.Nakano M. et al.Journal of Nutritional Science and Vitaminology, 2009; 55(4), 344-350.